NEWS

4th CUTANEOUS LYMPHOMA SYMPHOSIUM (JUNE 20, 2013)

MOFFITT DINNER CME 5 TO 6 PM: CONTACT MARSHA.MOYER@MOFFITT.ORG

NEW DIAGNOSTIC AND PROGNOSTIC MARKERS

NOVEL CTCL THERAPIES

RADIATION THERAPY

CASE PRESENTATIONS

FACULTY: Hernani Cualing, L. Frank Glass, Lubomir Sokol, Pedro Horna, Michael Tomblyn, Naomi Johansen, Jean Pierre Galliani.

 

MOFFIT CUTANEOUS LYMPHOMA SEMINAR (09-22-2011)

IHCFLOW, Hernani Cualing MD gave a seminar on Atypical Lymphoid Infiltrates and the Hematopathology Workup to Clinicians, Pathologists, Dermatopathologists,Oncologist, Radiation Oncologist at Sideberns, New Hyde Park,Tampa, FL on November 13, 2011. Please see the brochure and the Power Point copy of the presentations.

Cutaneous Lymphoma Dinner Meeting
Saturday, November 12, 2011 
SideBern's Restaurant 
Tampa, Florida

5:00 pm – 6:00 pm Registration & Reception 
6:00 pm – 6:30 pm Clinical Staging and Prognosis of Mycosis Fungoides, L. Frank Glass, MD 
6:30 pm – 7:00 pm Radiation Therapy in CTCL, Robert Lavey, MD, MPH 
7:00 pm – 7:30 pm Dinner 
7:30 pm – 8:00 pm Cutaneous Hematopathology Consultation Case Mix Hernani D. Cualing, MD 
8:00 pm – 8:30 pm Emerging Systemic Therapies for CTCL, Lubomir Sokol, MD, PhD 
8:30 pm – 9:00 pm Dessert/Coffee & Closing Remarks Program Recap by L. Frank Glass, MD

 

NEW!!!!Springer textbook: CUTANEOUS HEMATOPATHOLOGY. EDS. Hernani Cualing, Marshall Kadin, Mai Hoang, Michael Morgan. Approach to Lymphoma and Lymphoid Hyperplasia. 2014 publication.

Includes Tropical Cutaneous Infections. Partial List of Authors: Uma Sundram,Vincent Liu,  Manojkumar Patel, Mark Mochel, Meera Mahalingam, Alicia Schnebelen, Sara Shalin, M. Angelica Selim, May Chan, Wun Jun Shieh, Lubomir Sokol.Jonathan Lee

BOOK publication  (03-27-2012)

The book manuscript project headed by Hernani Cualing - a multi-author publication commisioned by WILEY-BLACKWELL for 2011 has concluded phase I- . Helped by CDC, Universities, private practitioners and corporate contributions from US and International contributors

NON NEOPLASTIC HEMATOPATHOLOGY AND INFECTIONS

2012 WILEY BLACKWELL PRINT AND E-BOOK FIRST EDITION

Many infectious agents disseminate in blood and the lymphatic system, and many of these infections are also tropical diseases that affect a large segment of the world's population, including travelers, immigrants, and refugees. The authors have carefully incorporated in this new book those diseases found in both Western and Eastern hemispheres, in order to assist pathologists and medical laboratory professionals all over the world to better diagnose and treat infections that may be expected, or indeed quite unusual for a given geographic region. The book features a wide range of non-neoplastic hematologic disorders, as well as reactive patterns of non-infectious and infectious agents, all thoroughly illustrated with photographs, tables and text. In addition to the comprehensive and state-of-the-art diagnostic materials, the epidemiology, pathobiology, clinical and pathologic manifestations in blood and lymphatic organs, as well as approaches to treatment, are also described.

Edited By Hernani Cualing
Format: Hardcover
Publisher: WILMD
ISBN-10: 0470646004
ISBN-13: 9780470646007

Associate-Editors: Parul Bhargava, Ramon Sandin Forewords: Bertram Schnitzer and James Smith

 

Automated Counting Cells in 1000 slides Licensed to Researchers

Technology Solutions for RESEARCH

 ‘Virtual’ flow cytometry: objective counting of cells licensed to JMC Surgery ENT Dr. Luginbuhl for easy counting of stromal cells

A new method could provide an important quantitative tool for research scientists and clinical researchers who need a tool to count cells in an automated rapid and objective manner.

 Recently, a medical student interning with Dr. Adam contacted IHCFLOW and presented to us a problem common in research facilities: counting immunostained cells in about a thousand of microscopic slides. Not daunted by the task of manually counting, the student nevertheless ask the question, is there a better way to go through the slides in a systematic, objective, real time operation short of manually drawing grids on the glass slides and counting cells inside the grids. They were interested in counting Heme Oxidase and VEGF positive cells, see below for some results.

On Feb 21, 2012, he sent us this email:

“My name is Giuseppe and I am a medical student researching at Jefferson Medical College. I am looking for software solutions to analyzing the cell number on virtual slides stained with IHC . Can your product analyze cells stained with H&E, and with DAB staining? I need a simple positive cell count. Do you have a trial software that I could use to see if it would work on my slides. I have 1000 (approx) slides that need to be analyzed for a cell count. There is some variance in terms of background and over-staining.

He sent us 4 images to play with initially and subsequently we trained the virtual Flow with more images and a sample data validation with images shown below after several iteration of custom software training and revalidations. After validation, the department acquired the license to use the technology for its research on July 2012.

 

HCFLOW PATENT CERTIFICATE PUBLISHED (07-04-2011)

Patent PUBLISHED!

The USPTO issued a certificate of awarded patent to IHCFLOW on March 1, 2011. The award is issued to inventors Hernani Cualing and Eric Zhong. The patent was written, prosecuted, and argued directly by Hernani Cualing pro se vis a vis expert patent examiner John Brusca. Extension to the decades long lifetime of the patent is also given.

View patent certificate copy here: page 1 page 2 page 3 page 4

BONE MARROW CELLULARITY PATENT PUBLICATION (09-25-2010)

International Patent Application Publication of Bone Marrow Cellularity Automated Determination

BONE MARROW CELLULARITY DETERMINATION PATENT click here

HCFLOW LINK ON FACEBOOK (09-25-2011)

A link for facebook is created by IHCFLOW, a company specializing in advancing the science and practice of diagnostic microscopy and hematopathology.

PATENTS AND INTELECTUAL PROPERTY (09-22-2011)

USPTO Awards Patent To Inventors- Virtual Flow- Tissue Cytometry

VirtualFlow Patent click here

BM Cellularity International Patent click here

USPTO VirtualFlowPatentedApplication click here

Provisional Reticulin Patent application click here 

Reticullin determination in bone marrow click here 

PHOTONICS NEWS: VIRTUALFLOW (09-22-2010)

VirtualFlow cytometry: Advanced Patented Technology- Sophisticated Yet Accessible- Gary Boas, Editor Photonics Magazine click here

VirtualFlow for use in counting CD30 lymphoma cells for research use click here 

WEBSITE CREATED! (09-21-2010)

Thank You for visiting this website!

Set of Modules for Hematopathology is created by IHCFLOW Inc and GreenGreat Technologies, Inc. Ten modules are available. VirtualFlow is the flagship module recently approved by USPTO as innovative, useful, nonobvious invention. The key difference between these set of modules with all extant and commercial pathology digital application is the ability of the software to mimic a flow cytometry functionality. This application, however, unlike flow cytometry uses tissue that has been fixed and stained by conventional means and does not require fresh tissue. This application allows the pathologist to provide a metric- not just an estimate of positive or negative results- to biopsy material- whether it is a bone marrow, a lymph node, a spleen, or any extranodal tissue.

The technology is engineered to be non-disruptive and seamlessly obey the work flow of a pathologist in daily diagnostic microscopic sign out activity. Because of these capability- it is a pioneering application- that removes the guess work out of diagnosis or estimate of immunohistochemisty, immunofluorescence, bone marrow cellularity, bone marrow reticulin, bone marrow immunohistochemistry, lymph node or any tissue immunohistochemistry for virtually all antibody available in the laboratory- whether the antibody is nuclear, cytoplasmic or membrane reactive- all of these special studies are converted to a numeric positive,negative and percent results: metrics that are not available with any other computerized image analysis or device. In addition, any other commercial image analysis, archiving, spectral imaging products out there are compatible with virtualFlow Cytometry.

Please contact the company for a demo or explanation for these applications.

OTHER NEWS

Moffitt Cutaneous Lymphoma Seminar: click here

Brochure and Contact Details click here

Cutaneous Lymphoma News and Publications

Upcoming Symposium 2011 Cutaneous Lymphoma Study Group H Cualing F Glass L Sokol

Cutaneous Lymphoma Symposia click here

Role of Immunophenotyping in Diagnosis, Staging and Targeted therapy of Cutaneous Lymphomas (CTCL and CBCL)

Hernani Cualing, MD Course Director 2nd Annual Cutaneous Lymphoma Seminar April 20 and 21, 2009 Buena Vista Lake Resort, Orlando FL

Sponsored by Moffitt Cancer Center and USF CME Office Eisai, Genentech, Genzyme, Cutaneous Lymphoma Foundation Cutaneous Lymphoma Study Group, USF/MCC collaborative Pathology, Dermatopathology, Heme Onc Faculty

Faculty: Blood Bank, Infectious Disease, Heme Onc, Lymphoma Vaccine, Pathology, Dermatology, Dermatopathology, Boston University Dermatology Department of Pathology and Cell Biology, University of South Florida College of Medicine

CTCL ETC LECTURE

Lymphoma lectures

ATYPICAL LYMPHOID INFILTRATES SYMPOSIUM POWERPOINT click here

T and B cell lymphoma, skin click here

T CELL LYMPHOMA

Cualing Lymphoma Documents

PTCL rare aggressive skin lymphomas other than CTCL mycosis fungoides click here

CD30 Lymphomas click here

Transplantation and T cell lymphomas click here

Photos of Langerhan cell hyperplasia and others click here

Presentations on CTCL and Lymphomas CTCL click here

Cutaneous B cell lymphomas click here

Research on Cutaneous Lymphomas Traf1 LyP click here